Sometimes the cancer cannot be found in the breast but cancer cells have spread to lymph nodes in the armpit. The grade describes how a cancer cell looks under the microscope and whether they are similar or very different to normal cells.
There are different systems used in the UK to stage breast cancer.
Breast cancer stage or grade. Many different factors are considered before doctors can confirm your final stage. TNM was adopted by the American Joint Committee on Cancer AJCC and issued their first edition in1977. The breast cancer has been detected in the early stages and can be very effectively treated.
Stage is a prognostic factor and in broad generalization low stage cancers Stages 0-II tend to have better long term outcome than high stage cancers Stages III-IV. The grade is used to help predict your outcome prognosis and to help figure out what treatments might work best. Understanding a patients stage helps the clinical team determine the right treatment.
Please remember staging for breast cancer is very complex. The staging system for breast cancer is complex so ask your doctor to explain how it applies to you. The grading system thats usually used is as follows.
As a rule the lower the number the less the cancer has spread. They are called HER2 positive cancers. It means the cancer is larger than 5 cm has spread to tissues around the breast such as the skin muscle or ribs or has spread to a large number of lymph nodes.
Doctors most often use the Nottingham grading system also called the Elston-Ellis modification of the Scarff-Bloom-Richardson grading system for breast cancer. Doctors use the stage and grade of a cancer to help them decide which treatment you need. Stage 1 breast cancer is when the cancer is 2cm or smaller.
It then ranges from stage I 1 through IV 4. The earliest stage breast cancers are stage 0 carcinoma in situ. How much of the tumor tissue has normal breast milk duct structures.
Grading means how abnormal the cancer cells look under a microscope. Stage 3A Stage 3B and Stage 3C. Although there were refinements breast cancer staging remained substantially the same over 60 years.
Stage 2 breast cancer is when the cancer is up to or bigger than 5cm. TNM was adopted by the Union for International Cancer Control UICC in the 1950s. This stage is divided into three groups.
And within a stage an earlier letter means a lower stage. HER2 makes the cancer cells grow and divide. With stage 1B breast cancer the tumor is less.
Cancer cells are given a grade when they are removed from the breast and checked in the lab. Stage 3A Breast Cancer Means One Of The Following Descriptions Applies. A stage IIB breast tumor is bigger — it may be the size of a walnut or as big as a lime.
Breast cancers that are HER2 positive generally grow more quickly. There may be no cancer cells in the lymph nodes in the armpit or tiny numbers of cancer cells are found. Read more on treatment options for stage II breast cancer.
Your pathology report will rate the cancer on a. The higher the stage number the larger the tumor and the more it has spread. Stage I through Stage III are for cancers that havent spread beyond the primary tumor site or have only spread to nearby tissue.
A higher number such as stage IV means cancer has spread more. An evaluation of the size and shape of the nucleus in the tumor cells. Staging means how big the cancer is and whether it has spread.
Grade is a score that tells you how different the cancer cells appearance and growth patterns are from those of normal healthy breast cells. A lower grade number 1 usually means the cancer is slower-growing and less likely to spread. The grade is based on how much the cancer cells look like normal cells.
About breast cancer staging and grades. Stage 1 can be divided into Stage 1A and Stage 1B. In stage 1A breast cancer the tumor measures up to 2 centimeters but theres no lymph node involvement.
The difference is determined by the size of the tumor and whether cancer has spread to the lymph nodes and surrounding tissue. Stage 1 is divided into stages 1A and 1B. In Stage 1 breast cancer cancer is evident but it is contained to only the area where the first abnormal cells began to develop.
It may or may not be in any lymph nodes. Breast cancer stage ranges from Stage 0 pre-invasive disease to Stage IV metastatic disease. This system grades breast tumors based on the following features.
Locally advanced breast cancer is stage 3. Grade I cancer cells that resemble normal cells and arent growing rapidly grade II cancer cells that dont look like normal cells and are growing faster than normal cells grade III cancer cells that look abnormal and may grow or spread more aggressively.